Asset profile

Reboxetine

Small molecule

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Phase 3underway

Evidence outlook · registrational

Narcolepsy: registrational readout pending

Its supporting mid-stage evidence has not yet been graded on this platform. No upcoming registrational readout date is posted to the registry. Check News for topline announcements.

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Competitive landscape

5 competitors in this universe: 0 direct rivals (same mechanism and indication), 1 same-class, 4 same-indication; 3 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Reboxetine: this drugPhase 3Small moleculenorepinephrine transporter
Ampreloxetine (TD-9855)Phase 3Small moleculenorepinephrine transporter
Pitolisant (Wakix)ApprovedSmall moleculeHistamine H3 receptor (antagonist / inverse agonist)
Sodium OxybateApprovedSmall moleculeGABA-B receptor
Solriamfetol (Sunosi)ApprovedSmall moleculeDopamine/norepinephrine transporter
ALKS 2680Phase 3Small molecule—
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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(1 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2028 (1)
August 2028 (1)
Phase 2PTSD, Posttraumatic Stress DisorderRecruiting
Est. primary completion 2028-08-01 · NCT07771530 · CT.gov ↗
What to watch
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All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (2)
Phase 2 (2)
Phase 1 (2)
Phase 4 (2)
Early phase / not applicable (2)