Asset profile

ONO-1110

Small molecule

Partialsignal

Evidence outlook · lead readout

NCT06792136 · Major Depressive Disorder (MDD

The completed lead evidence is positive, with design limits that temper confidence — see the rationale below for exactly which.

NCT06792136: The trial randomized 103 participants to ONO-1110 or placebo and masked both participants and investigators. Its primary endpoint was change in the clinical HAM-D17 depression score at Week 8, but results are not posted, so whether the primary endpoint was met is unknown.

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