Asset profile

Naltrexone (Vivitrol)

Small molecule

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Approvedregulatory verdict

Evidence outlook

Approved: Opioid and Alcohol Dependence

Regulatory approval supersedes design-level evidence grading; the trials behind approval are preserved below as the drug's evidence history.

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Competitive landscape

1 competitor in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 1 same-indication.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Naltrexone (Vivitrol): this drugApprovedSmall moleculeOpioid receptor
NaltrexoneApproved—Opioid receptors (mu-opioid receptor)
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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(2 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (1)
December 2026 (1)
Phase 1Healthy Adult Male and Female VolunteersRecruiting
Est. primary completion 2026-12-05 · NCT07269873 · CT.gov ↗
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2029 (1)
October 2029 (1)
Phase 1Opioid Use DisorderActive not recruiting
Est. primary completion 2029-10-01 · NCT07064564 · CT.gov ↗
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All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (15)
Phase 2/3 (2)
Phase 2 (7)
Phase 1 (5)
Phase 4 (7)
Early phase / not applicable (2)
Used as active comparator (3)