Asset profile

Methotrexate

Unknown / undisclosed

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Approvedregulatory verdict

Evidence outlook

Approved: Rheumatoid Arthritis

Regulatory approval supersedes design-level evidence grading; the trials behind approval are preserved below as the drug's evidence history.

track record: Partial signal

How the evidence outlook works ↗

Competitive landscape

60 competitors in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Methotrexate: this drugApproved—Dihydrofolate reductase (DHFR), Folate Analog Metabolic Inhibitor
Abatacept (Orencia)ApprovedProtein / enzyme therapeuticCD80/CD86 (CTLA-4-Ig), Selective T Cell Costimulation Modulator, CD80/CD86 (B7-1/B7-2) on antigen-presenting cells
Adalimumab (Humira)ApprovedMonoclonal antibodyTNF-alpha
Adalimumab-Adbm (Cyltezo)ApprovedMonoclonal antibodyTNF-alpha
Adalimumab-Ryvk (Simlandi)Approved—TNF-alpha
Aldesleukin (Proleukin)ApprovedRecombinant Cytokine (il-2)Interleukin-2 receptor (IL-2R)
Anakinra (r-metHuIL-1ra)ApprovedProtein / enzyme therapeuticInterleukin-1 receptor (IL-1R), Interleukin-1 receptor type 1 (IL-1R1)
Baricitinib (Olumiant)ApprovedSmall moleculeJAK, JAK1/2
Certolizumab Pegol (Cimzia)ApprovedAntibody fragmentTNF-alpha
CT-P13 (Inflectra / Remsima)ApprovedMonoclonal antibodyTNF-alpha
CT-P47 (tocilizumab) (Avtozma)ApprovedMonoclonal antibodyIL-6R antagonist
DenosumabApprovedMonoclonal antibodyRANKL
Etanercept (Enbrel)ApprovedProtein / enzyme therapeuticTNF-alpha, TNF-alpha / TNF-beta (lymphotoxin-alpha)
Golimumab (Simponi)ApprovedMonoclonal antibodyTNF-alpha
HZT-501 (Duexis)ApprovedSmall moleculeCyclooxygenase (COX-1/COX-2) plus histamine H2 receptor
Infliximab (Remicade)ApprovedMonoclonal antibodyTNF-alpha

…and 45 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(147 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (29)
October 2026 (3)
Phase 4Psoriasis, PruritusNot yet recruiting
Est. primary completion 2026-10-14 · NCT07432386 · CT.gov ↗
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Early phase / not applicableChemotherapy Induced Oral MucositisNot yet recruiting
Est. primary completion 2026-10-30 · NCT07327476 · CT.gov ↗
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Phase 2T Acute Lymphoblastic Leukemia, T Lymphoblastic LymphomaRecruiting
Est. primary completion 2026-10-31 · NCT00501826 · CT.gov ↗
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November 2026 (9)
Phase 2CNS LymphomaNot yet recruiting
Est. primary completion 2026-11 · NCT06901999 · CT.gov ↗
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Phase 2Sickle Cell DiseaseActive not recruiting
Est. primary completion 2026-11 · NCT04018937 · CT.gov ↗
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Phase 3Moderate to Severe Atopic DermatitisRecruiting
Est. primary completion 2026-11 · NCT06239311 · CT.gov ↗
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Phase 2Acute Lymphoblastic LeukemiaRecruiting
Est. primary completion 2026-11-01 · NCT05519579 · CT.gov ↗
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Phase 2B Acute Lymphoblastic Leukemia, B Lymphoblastic LymphomaRecruiting
Est. primary completion 2026-11-01 · NCT02877303 · CT.gov ↗
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Early phase / not applicableMalignant Bone TumorRecruiting
Est. primary completion 2026-11-01 · NCT06302465 · CT.gov ↗
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Phase 1Healthy VolunteersRecruiting
Est. primary completion 2026-11-07 · NCT07446400 · CT.gov ↗
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Phase 3Acute Lymphoblastic Leukemia, PediatricActive not recruiting
Est. primary completion 2026-11-30 · NCT03020030 · CT.gov ↗
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Early phase / not applicableVitiligoNot yet recruiting
Est. primary completion 2026-11-30 · NCT06877455 · CT.gov ↗
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December 2026 (17)
Phase 1Breast CancerRecruiting
Est. primary completion 2026-12 · NCT02897700 · CT.gov ↗
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Phase 2GVHD,Acute, Acute Leukemia, Myelodysplastic Syndromes, Myeloproliferative DisordersRecruiting
Est. primary completion 2026-12 · NCT06315309 · CT.gov ↗
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Phase 3Cardiac Sarcoidosis, SarcoidosisRecruiting
Est. primary completion 2026-12 · NCT03593759 · CT.gov ↗
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Phase 4Hand Osteoarthritis, Erosive OsteoarthritisActive not recruiting
Est. primary completion 2026-12 · NCT04579848 · CT.gov ↗
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Phase 1/2Acute Leukemia, Lymphoblastic Leukemia, Lymphoblastic LymphomaRecruiting
Est. primary completion 2026-12-01 · NCT06207123 · CT.gov ↗
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Phase 2Precursor Cell Lymphoblastic Leukemia-LymphomaRecruiting
Est. primary completion 2026-12-01 · NCT06387121 · CT.gov ↗
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Phase 4Depression, Anxiety, PsoriasisRecruiting
Est. primary completion 2026-12-01 · NCT07432815 · CT.gov ↗
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Early phase / not applicableChronic Plaque PsoriasisNot yet recruiting
Est. primary completion 2026-12-01 · NCT07581418 · CT.gov ↗
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Phase 2Leptomeningeal Metastasis of Breast CancerRecruiting
Est. primary completion 2026-12-13 · NCT06543992 · CT.gov ↗
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Phase 1GoutRecruiting
Est. primary completion 2026-12-30 · NCT06298071 · CT.gov ↗
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Phase 1Lymphoma, Primary Central Nervous System LymphomaRecruiting
Est. primary completion 2026-12-30 · NCT06475235 · CT.gov ↗
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Phase 2Diffuse Large B-cell LymphomaRecruiting
Est. primary completion 2026-12-30 · NCT05257018 · CT.gov ↗
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Phase 1/2Leptomeningeal Metastasis From Lung CancerRecruiting
Est. primary completion 2026-12-31 · NCT07559097 · CT.gov ↗
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Phase 2Blastic Plasmacytoid Dendritic Cell NeoplasmRecruiting
Est. primary completion 2026-12-31 · NCT04216524 · CT.gov ↗
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Phase 2Recurrent B Acute Lymphoblastic Leukemia, Recurrent B Lymphoblastic Lymphoma, Refractory B Acute Lymphoblastic Leukemia …Active not recruiting
Est. primary completion 2026-12-31 · NCT02981628 · CT.gov ↗
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Phase 3T-cell Lymphoblastic LymphomaRecruiting
Est. primary completion 2026-12-31 · NCT05681260 · CT.gov ↗
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Phase 4Rheumatoid ArthritisActive not recruiting
Est. primary completion 2026-12-31 · NCT05353829 · CT.gov ↗
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2027 (49)
January 2027 (3)
Phase 2Vulvar Lichen SclerosusRecruiting
Est. primary completion 2027-01 · NCT07352917 · CT.gov ↗
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Phase 2Rheumatoid ArthritisNot yet recruiting
Est. primary completion 2027-01-15 · NCT06590090 · CT.gov ↗
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Phase 2Caesarean Scar PregnancyNot yet recruiting
Est. primary completion 2027-01-20 · NCT07288307 · CT.gov ↗
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February 2027 (3)
Phase 2Non-Hodgkin LymphomaRecruiting
Est. primary completion 2027-02 · NCT05583071 · CT.gov ↗
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Early phase / not applicablePrimary Central Nervous System LymphomaRecruiting
Est. primary completion 2027-02-13 · NCT06832267 · CT.gov ↗
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Phase 2Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia With BCR-ABL1 …Active not recruiting
Est. primary completion 2027-02-28 · NCT03147612 · CT.gov ↗
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March 2027 (4)
Phase 2Acute Lymphoblastic Leukemia, Philadelphia Chromosome-PositiveActive not recruiting
Est. primary completion 2027-03 · NCT04329325 · CT.gov ↗
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Phase 3B Acute Lymphoblastic LeukemiaRecruiting
Est. primary completion 2027-03-01 · NCT03150693 · CT.gov ↗
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Phase 4Rheumatoid ArthritisNot yet recruiting
Est. primary completion 2027-03-05 · NCT07636057 · CT.gov ↗
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Phase 2Mantle Cell LymphomaActive not recruiting
Est. primary completion 2027-03-22 · NCT03710772 · CT.gov ↗
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April 2027 (6)
Early phase / not applicablePrimary Central Nervous System LymphomaNot yet recruiting
Est. primary completion 2027-04 · NCT07406230 · CT.gov ↗
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Phase 1Primary Diffuse Large B-Cell Lymphoma of the Central Nervous SystemActive not recruiting
Est. primary completion 2027-04-01 · NCT04609046 · CT.gov ↗
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Phase 2B Acute Lymphoblastic Leukemia, B Lymphoblastic LymphomaActive not recruiting
Est. primary completion 2027-04-01 · NCT05303792 · CT.gov ↗
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Phase 1B Acute Lymphoblastic Leukemia, Ph-Like Acute Lymphoblastic LeukemiaActive not recruiting
Est. primary completion 2027-04-12 · NCT05157971 · CT.gov ↗
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Phase 2Rheumatoid ArthritisRecruiting
Est. primary completion 2027-04-15 · NCT07409103 · CT.gov ↗
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Phase 2Hematopoietic and Lymphatic System NeoplasmRecruiting
Est. primary completion 2027-04-30 · NCT06895473 · CT.gov ↗
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June 2027 (4)
Phase 2Polycythemia Vera (PV), Essential Thrombocythemia (ET), Myelofibrosis (MF)Recruiting
Est. primary completion 2027-06 · NCT06541249 · CT.gov ↗
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Phase 2Ectopic PregnancyNot yet recruiting
Est. primary completion 2027-06 · NCT07624903 · CT.gov ↗
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Phase 3Mature B-cell Non-Hodgkin LymphomaActive not recruiting
Est. primary completion 2027-06 · NCT03206671 · CT.gov ↗
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Phase 2Blastoid Variant Mantle Cell Lymphoma, Mantle Cell Lymphoma, Pleomorphic Variant Mantle Cell LymphomaActive not recruiting
Est. primary completion 2027-06-30 · NCT02427620 · CT.gov ↗
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July 2027 (1)
Phase 2Relapsing PolychondritisRecruiting
Est. primary completion 2027-07 · NCT06941376 · CT.gov ↗
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August 2027 (3)
Phase 2NeuroblastomaNot yet recruiting
Est. primary completion 2027-08 · NCT05303727 · CT.gov ↗
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Phase 2LeukemiaActive not recruiting
Est. primary completion 2027-08 · NCT01920737 · CT.gov ↗
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Phase 3Investigate the Effect(s) of Methotrexate Treatment on Arthritis Disease SeverityActive not recruiting
Est. primary completion 2027-08-30 · NCT04483466 · CT.gov ↗
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September 2027 (4)
Early phase / not applicableLymphoma CnsRecruiting
Est. primary completion 2027-09-02 · NCT07191431 · CT.gov ↗
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Phase 2/3Renal Pelvis and Ureter Urothelial CarcinomaRecruiting
Est. primary completion 2027-09-30 · NCT04628767 · CT.gov ↗
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Phase 3B Acute Lymphoblastic Leukemia, B Lymphoblastic Lymphoma, Down SyndromeActive not recruiting
Est. primary completion 2027-09-30 · NCT03914625 · CT.gov ↗
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Phase 4PhenylketonuriaRecruiting
Est. primary completion 2027-09-30 · NCT07477691 · CT.gov ↗
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October 2027 (3)
Phase 2Graft Versus Host Disease, Hematologic MalignancyRecruiting
Est. primary completion 2027-10-18 · NCT06252870 · CT.gov ↗
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Phase 2Primary Intraocular LymphomaRecruiting
Est. primary completion 2027-10-30 · NCT06973811 · CT.gov ↗
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Phase 2Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Lymphoblastic Leukemia …Active not recruiting
Est. primary completion 2027-10-31 · NCT01424982 · CT.gov ↗
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November 2027 (3)
Phase 1Central Nervous System LymphomaActive not recruiting
Est. primary completion 2027-11 · NCT03684980 · CT.gov ↗
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Phase 4Alopecia Areata(AA), Alopecia Areata (AA), Alopecia Totalis/Universalis, Alopecia Universalis (AU), Alopecia Totalis (AT) …Recruiting
Est. primary completion 2027-11-01 · NCT07381556 · CT.gov ↗
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Phase 2Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Lymphoblastic Leukemia, BCR-ABL1 Fusion Protein Expression …Recruiting
Est. primary completion 2027-11-30 · NCT03263572 · CT.gov ↗
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December 2027 (15)
Phase 2T-cell Acute Lymphoblastic Leukemia, T-cell Lymphoma, Mixed Phenotype Acute LeukemiaRecruiting
Est. primary completion 2027-12 · NCT06390319 · CT.gov ↗
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Phase 2GoutRecruiting
Est. primary completion 2027-12 · NCT07280156 · CT.gov ↗
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Phase 4Juvenile Idiopathic ArthritisRecruiting
Est. primary completion 2027-12 · NCT06653634 · CT.gov ↗
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Early phase / not applicablePrimary Central Nervous System Lymphoma (PCNSL), CNS Lymphoma TreatmentRecruiting
Est. primary completion 2027-12-01 · NCT06946407 · CT.gov ↗
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Phase 1B Acute Lymphoblastic Leukemia, B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1, Mixed Phenotype Acute Leukemia …Active not recruiting
Est. primary completion 2027-12-02 · NCT04872790 · CT.gov ↗
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Phase 2Precursor Cell Lymphoblastic Leukemia-LymphomaRecruiting
Est. primary completion 2027-12-15 · NCT05660473 · CT.gov ↗
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Phase 1/2B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1, B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative …Recruiting
Est. primary completion 2027-12-25 · NCT01371630 · CT.gov ↗
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Phase 4Autoimmune Rheumatic DiseasesRecruiting
Est. primary completion 2027-12-30 · NCT07242092 · CT.gov ↗
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Phase 1NK-Cell Lymphoma, NK-Cell Leukemia, Peripheral T Cell LymphomaRecruiting
Est. primary completion 2027-12-31 · NCT03719105 · CT.gov ↗
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Phase 2Recurrent Acute Leukemia of Ambiguous Lineage, Recurrent Acute Lymphoblastic Leukemia …Active not recruiting
Est. primary completion 2027-12-31 · NCT05761171 · CT.gov ↗
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Phase 2Acute Leukemia, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Myelodysplastic Syndrome, Myeloproliferative NeoplasmRecruiting
Est. primary completion 2027-12-31 · NCT03970096 · CT.gov ↗
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Phase 2LeukemiaRecruiting
Est. primary completion 2027-12-31 · NCT05645718 · CT.gov ↗
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Phase 4Rheumatoid ArthritisRecruiting
Est. primary completion 2027-12-31 · NCT06913907 · CT.gov ↗
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Phase 4Psoriatic Arthritis (PsA)Recruiting
Est. primary completion 2027-12-31 · NCT07486843 · CT.gov ↗
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Early phase / not applicableImmunoclassification, PsoriasisRecruiting
Est. primary completion 2027-12-31 · NCT05503875 · CT.gov ↗
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2028 (38)
January 2028 (4)
Phase 2Rheumatic DiseaseRecruiting
Est. primary completion 2028-01 · NCT07138898 · CT.gov ↗
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Phase 2Primary Central Nervous System Lymphoma (PCNSL), Non Hodgkin Lymphoma (NHL)Not yet recruiting
Est. primary completion 2028-01-01 · NCT06646211 · CT.gov ↗
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Phase 2/3NPC, HNSCC, Recurrence, MetastasisNot yet recruiting
Est. primary completion 2028-01-01 · NCT06719479 · CT.gov ↗
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Phase 2LymphomaRecruiting
Est. primary completion 2028-01-09 · NCT07015242 · CT.gov ↗
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February 2028 (2)
Phase 2/3Erosive Hand OsteoarthritisRecruiting
Est. primary completion 2028-02 · NCT07501507 · CT.gov ↗
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Phase 4Idiopathic Granulomatous MastitisNot yet recruiting
Est. primary completion 2028-02-01 · NCT06943482 · CT.gov ↗
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March 2028 (5)
Phase 2Osteosarcoma, MetastasisRecruiting
Est. primary completion 2028-03 · NCT07477457 · CT.gov ↗
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Phase 3Rheumatoid ArthritisRecruiting
Est. primary completion 2028-03 · NCT03414502 · CT.gov ↗
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Phase 2Lymphoblastic Leukemia, Acute Lymphoblastic Leukemia, ph+ Acute Lymphoblastic LeukemiaRecruiting
Est. primary completion 2028-03-01 · NCT04747912 · CT.gov ↗
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Phase 1Recurrent Childhood Acute Myeloid Leukemia, Recurrent Childhood Myelodysplastic Syndrome, Recurrent Juvenile Myelomonocytic Leukemia …Recruiting
Est. primary completion 2028-03-31 · NCT06247787 · CT.gov ↗
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Phase 2Down Syndrome, Acute Lymphoblastic Leukemia, Childhood CancerActive not recruiting
Est. primary completion 2028-03-31 · NCT03286634 · CT.gov ↗
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April 2028 (1)
Phase 1Primary Central Nervous System LymphomaActive not recruiting
Est. primary completion 2028-04-28 · NCT06541665 · CT.gov ↗
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May 2028 (3)
Phase 2Acute Lymphoblastic Leukemia, Lymphoblastic LymphomaRecruiting
Est. primary completion 2028-05 · NCT06533748 · CT.gov ↗
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Phase 2Ph- Acute Lymphoblastic Leukemia (Ph-ALL)Not yet recruiting
Est. primary completion 2028-05-31 · NCT07643103 · CT.gov ↗
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Phase 2Non-hodgkin LymphomaRecruiting
Est. primary completion 2028-05-31 · NCT05998642 · CT.gov ↗
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June 2028 (5)
Phase 2Acute Myeloid Leukemia in ChildrenRecruiting
Est. primary completion 2028-06 · NCT06262438 · CT.gov ↗
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Phase 2/3Childhood EpendymomaRecruiting
Est. primary completion 2028-06 · NCT02265770 · CT.gov ↗
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Phase 3Primary Central Nervous System LymphomaActive not recruiting
Est. primary completion 2028-06 · NCT04931368 · CT.gov ↗
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Phase 3Uncontrolled GoutRecruiting
Est. primary completion 2028-06-18 · NCT07388498 · CT.gov ↗
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Phase 2Down Syndrome, Recurrent B Acute Lymphoblastic LeukemiaRecruiting
Est. primary completion 2028-06-30 · NCT04546399 · CT.gov ↗
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July 2028 (4)
Phase 1Muscle Invasive Bladder Urothelial CarcinomaEnrolling by invitation
Est. primary completion 2028-07-01 · NCT06204614 · CT.gov ↗
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Phase 3B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1Active not recruiting
Est. primary completion 2028-07-01 · NCT04530565 · CT.gov ↗
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Phase 1Myelodysplastic Syndromes, de Novo, Myelodysplastic Syndromes, Secondary, Myelodysplastic Syndromes, Previously Treated …Recruiting
Est. primary completion 2028-07-02 · NCT05292664 · CT.gov ↗
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Phase 3Acute Lymphoblastic Leukemia, PediatricRecruiting
Est. primary completion 2028-07-14 · NCT03643276 · CT.gov ↗
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August 2028 (3)
Phase 2Acute Leukemia, Myelodysplastic Syndrome, Myeloproliferative DisordersRecruiting
Est. primary completion 2028-08 · NCT06265584 · CT.gov ↗
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Early phase / not applicablePrimary Central Nervous System Lymphoma, Diffuse Large B-Cell LymphomaNot yet recruiting
Est. primary completion 2028-08 · NCT07764601 · CT.gov ↗
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Phase 2Urothelial Carcinoma, Bladder CancerActive not recruiting
Est. primary completion 2028-08-31 · NCT05137262 · CT.gov ↗
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September 2028 (1)
Phase 2/3Primary Central Nervous System LymphomaRecruiting
Est. primary completion 2028-09-30 · NCT07185373 · CT.gov ↗
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October 2028 (1)
Phase 3Urinary Bladder Neoplasms, Immune Checkpoint Inhibitors, Methotrexate, Vinblastine, Doxorubicin, Cisplatin, GemcitabineRecruiting
Est. primary completion 2028-10-31 · NCT06960577 · CT.gov ↗
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December 2028 (9)
Phase 1/2Lymphoblastic LeukemiaRecruiting
Est. primary completion 2028-12 · NCT05848687 · CT.gov ↗
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Phase 2Osteosarcoma in Children, Osteosarcoma in Adolescents and Young AdultsRecruiting
Est. primary completion 2028-12 · NCT07560826 · CT.gov ↗
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Phase 2LymphomasRecruiting
Est. primary completion 2028-12-30 · NCT07002099 · CT.gov ↗
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Phase 2PCNSL, Primary Central Nervous System LymphomaRecruiting
Est. primary completion 2028-12-31 · NCT07350850 · CT.gov ↗
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Phase 2Primary Central Nervous System Lymphoma (PCNSL), Secondary Central Nervous System Lymphoma (SCNSL)Recruiting
Est. primary completion 2028-12-31 · NCT07410520 · CT.gov ↗
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Phase 2Acute Biphenotypic Leukemia, Acute Leukemia, Acute Leukemia of Ambiguous Lineage, Acute Lymphoblastic Leukemia …Recruiting
Est. primary completion 2028-12-31 · NCT03779854 · CT.gov ↗
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Phase 2Acute Lymphoblastic LeukemiaNot yet recruiting
Est. primary completion 2028-12-31 · NCT07301138 · CT.gov ↗
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Phase 2Central Nervous System Lymphoma, Secondary Central Nervous System LymphomaActive not recruiting
Est. primary completion 2028-12-31 · NCT03964090 · CT.gov ↗
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Phase 2Acute Leukemia of Ambiguous Lineage, B Acute Lymphoblastic LeukemiaRecruiting
Est. primary completion 2028-12-31 · NCT06317662 · CT.gov ↗
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2029 (8)
March 2029 (2)
Phase 1Multiple MyelomaActive not recruiting
Est. primary completion 2029-03 · NCT04960579 · CT.gov ↗
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Phase 2B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative, Lymphoblastic LymphomaRecruiting
Est. primary completion 2029-03-30 · NCT06918431 · CT.gov ↗
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May 2029 (2)
Phase 4Rheumatoid ArthritisRecruiting
Est. primary completion 2029-05-01 · NCT07802678 · CT.gov ↗
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Phase 2/3Rheumatoid ArthritisRecruiting
Est. primary completion 2029-05-31 · NCT07627893 · CT.gov ↗
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June 2029 (1)
Phase 3Acute Myeloid LeukemiaRecruiting
Est. primary completion 2029-06-30 · NCT04293562 · CT.gov ↗
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August 2029 (1)
Phase 2Metastatic Oral Cavity Carcinoma, Recurrent Oral Cavity Carcinoma, Stage IVC Lip and Oral Cavity Cancer AJCC v8, Head and Neck Cancer …Recruiting
Est. primary completion 2029-08-05 · NCT06997068 · CT.gov ↗
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December 2029 (2)
Phase 3Severe Aplastic AnemiaActive not recruiting
Est. primary completion 2029-12 · NCT05600426 · CT.gov ↗
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Phase 2Leukemia, Myeloid, AcuteNot yet recruiting
Est. primary completion 2029-12-31 · NCT07686107 · CT.gov ↗
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2030 (10)
March 2030 (1)
Phase 2B Lymphoblastic LeukemiaRecruiting
Est. primary completion 2030-03 · NCT06336395 · CT.gov ↗
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April 2030 (2)
Phase 3Lymphoblastic Lymphoma, ChildhoodRecruiting
Est. primary completion 2030-04-22 · NCT04043494 · CT.gov ↗
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Phase 1CNS LymphomaRecruiting
Est. primary completion 2030-04-30 · NCT06730542 · CT.gov ↗
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June 2030 (2)
Phase 4Psoriasis, Atopic DermatitisNot yet recruiting
Est. primary completion 2030-06-01 · NCT07352566 · CT.gov ↗
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Phase 2/3Mature B-cell Non-Hodgkin LymphomaRecruiting
Est. primary completion 2030-06-30 · NCT07168980 · CT.gov ↗
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July 2030 (1)
Phase 2Acute Lymphoblastic Leukemia, Philadelphia Chromosome-Negative Lymphoblastic Leukemia, Acute Lymphoblastic Leukemia (ALL), LeukemiaRecruiting
Est. primary completion 2030-07-31 · NCT07227584 · CT.gov ↗
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August 2030 (1)
Phase 2Adenocarcinoma of the Breast, Breast Cancer, Triple Negative Breast CancerRecruiting
Est. primary completion 2030-08-11 · NCT07768436 · CT.gov ↗
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September 2030 (1)
Phase 2Myelodysplastic/Myeloproliferative Neoplasm, Primary Myelofibrosis, Secondary MyelofibrosisRecruiting
Est. primary completion 2030-09-01 · NCT07228624 · CT.gov ↗
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November 2030 (1)
Phase 2Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Myelodysplastic SyndromeRecruiting
Est. primary completion 2030-11-22 · NCT06128070 · CT.gov ↗
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December 2030 (1)
Phase 2B Acute Lymphoblastic LeukemiaRecruiting
Est. primary completion 2030-12-01 · NCT06124157 · CT.gov ↗
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2031 (4)
January 2031 (1)
Phase 3Graft-versus-host Disease (GVHD)Recruiting
Est. primary completion 2031-01-17 · NCT06615050 · CT.gov ↗
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April 2031 (1)
Phase 2Acute Leukemia of Ambiguous Lineage, B Acute Lymphoblastic Leukemia, B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative …Not yet recruiting
Est. primary completion 2031-04-16 · NCT07636564 · CT.gov ↗
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June 2031 (1)
Phase 2Osteosarcoma, Ewing SarcomaRecruiting
Est. primary completion 2031-06-01 · NCT07321912 · CT.gov ↗
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December 2031 (1)
Phase 3Extranodal NK/T-cell LymphomaRecruiting
Est. primary completion 2031-12-31 · NCT07678229 · CT.gov ↗
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2032 (1)
March 2032 (1)
Phase 3B Acute Lymphoblastic Leukemia, B Lymphoblastic Lymphoma, Central Nervous System Leukemia, Mixed Phenotype Acute Leukemia …Recruiting
Est. primary completion 2032-03-31 · NCT03959085 · CT.gov ↗
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2033 (3)
September 2033 (1)
Phase 1/2Acute Lymphoblastic Leukemia, Leukemia, Lymphoblastic, Acute, Philadelphia-Positive …Recruiting
Est. primary completion 2033-09-19 · NCT07387926 · CT.gov ↗
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November 2033 (1)
Phase 2/3Recurrent Burkitt Lymphoma, Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 Rearrangements, Refractory Burkitt Lymphoma …Not yet recruiting
Est. primary completion 2033-11-01 · NCT07724457 · CT.gov ↗
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December 2033 (1)
Phase 2Lymphoblastic Leukemia in ChildrenRecruiting
Est. primary completion 2033-12-31 · NCT06099366 · CT.gov ↗
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2034 (2)
May 2034 (1)
Phase 4Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma, Mixed Phenotype Acute LeukemiaRecruiting
Est. primary completion 2034-05 · NCT06289673 · CT.gov ↗
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September 2034 (1)
Phase 2Breast CancerRecruiting
Est. primary completion 2034-09 · NCT06085742 · CT.gov ↗
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2035 (2)
July 2035 (1)
Phase 2MedulloblastomaRecruiting
Est. primary completion 2035-07 · NCT05535166 · CT.gov ↗
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September 2035 (1)
Phase 2/3Stage II T Lymphoblastic Leukemia/Lymphoma, Stage III T Lymphoblastic Leukemia/Lymphoma, Stage IV T Lymphoblastic Leukemia/Lymphoma …Not yet recruiting
Est. primary completion 2035-09-01 · NCT07072585 · CT.gov ↗
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2038 (1)
December 2038 (1)
Phase 2Metastatic Colorectal CancerRecruiting
Est. primary completion 2038-12-31 · NCT05725200 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (310)
Phase 2/3 (40)
Phase 2 (545)
Phase 1/2 (75)
Phase 1 (133)
Phase 4 (184)
Early phase / not applicable (109)
Used as active comparator (98)
Appears in other studies (146)