Asset profile

Evorpacept

Protein / enzyme therapeutic

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Phase 3underway

Evidence outlook · registrational

Gastric Cancer: registrational readout pending

Its supporting mid-stage evidence has not yet been graded on this platform. The registry's posted readout date (2024-05-24) has passed without a status update. Check News for topline announcements.

Also in development:Multiple Myeloma

How the evidence outlook works ↗

Competitive landscape

64 competitors in this universe: 1 direct rival (same mechanism and indication), 1 same-class, 62 same-indication; 52 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Evorpacept: this drugPhase 2/3Protein / enzyme therapeuticCD47
MaplirpaceptPhase 2Protein / enzyme therapeuticCD47
AK117Phase 3Monoclonal antibodyCD47
Belantamab MafodotinApprovedAntibody–drug conjugateBCMA
BortezomibApprovedSmall moleculeProteasome
CarfilzomibApprovedSmall moleculeProteasome
Ciltacabtagene AutoleucelApprovedCell therapyBCMA
DaratumumabApprovedMonoclonal antibodyCD38
DenosumabApprovedMonoclonal antibodyRANKL
ElotuzumabApprovedMonoclonal antibodySLAMF7 (CS1/CD319)
ElranatamabApprovedMultispecific antibodyBCMA x CD3
Idecabtagene VicleucelApprovedCell therapyBCMA
IsatuximabApprovedMonoclonal antibodyCD38
IxazomibApprovedSmall moleculeProteasome
LenalidomideApprovedSmall moleculeCereblon E3 ubiquitin-ligase, Thalidomide Analog
LinvoseltamabApprovedMultispecific antibodyBCMA x CD3

…and 49 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(4 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (2)
September 2027 (1)
Phase 1/2Plasma Cell Myeloma RefractoryRecruiting
Est. primary completion 2027-09-13 · NCT04643002 · CT.gov ↗
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December 2027 (1)
Phase 2Breast Cancer, MetastaticRecruiting
Est. primary completion 2027-12 · NCT07007559 · CT.gov ↗
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2028 (1)
March 2028 (1)
Phase 1/2Aggressive B-Cell Non-Hodgkin Lymphoma, Ann Arbor Stage III Grade 2 Follicular Lymphoma, Ann Arbor Stage III Grade 3 Follicular Lymphoma …Active not recruiting
Est. primary completion 2028-03-21 · NCT05025800 · CT.gov ↗
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2030 (1)
December 2030 (1)
Phase 1/2HER2-positive Breast Cancer, Metastatic Cancer, Metastatic Breast Cancer, Metastatic, HER2-positive Metastatic Breast Cancer …Recruiting
Est. primary completion 2030-12-30 · NCT05868226 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 2/3 (1)
Phase 2 (6)
Phase 1/2 (4)
Phase 1 (4)