Asset profile

chloroprocaine

Small molecule

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Approvedregulatory verdict

Evidence outlook

Approved: Ocular Surface Anesthesia

Regulatory approval supersedes design-level evidence grading; the trials behind approval are preserved below as the drug's evidence history.

Also in development:Age-Related Macular Degeneration

How the evidence outlook works ↗

Competitive landscape

31 competitors in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 31 same-indication.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Chloroprocaine: this drugApprovedSmall moleculeVoltage-gated sodium channels (Nav) on sensory nerve membranes
Aflibercept (Eylea)ApprovedProtein / enzyme therapeuticVEGF-A, VEGF-A / VEGF-B / Placental Growth Factor (PlGF)
Avacincaptad Pegol (Izervay)ApprovedRna AptamerComplement C5
Brolucizumab-DbllApprovedMonoclonal antibodyVEGF-A
FaricimabApprovedMultispecific antibodyAngiopoietin-2 / VEGF-A
Pegaptanib (Macugen)ApprovedSmall moleculeVEGF-A
Pegcetacoplan Ophthalmic (Syfovre)ApprovedPeptideComplement C3, Complement C3 / C3b
Ranibizumab (Lucentis)ApprovedMonoclonal antibodyVEGF-A
VerteporfinApprovedSmall moleculeBenzoporphyrin-derivative photosensitizer for photodynamic therapy
VisudyneApprovedSmall moleculePhotosensitizing agent (photodynamic therapy)
ABBV-RGX-314Phase 3Gene therapy / editingVEGF-A
ABP 938Phase 3Protein / enzyme therapeuticVEGF-A / VEGF-B / PlGF
ANX007Phase 3Monoclonal antibodyComplement C1q
CemdisiranPhase 3RNA / oligonucleotideComplement C5
CKD-701Phase 3Monoclonal antibodyVEGF-A
HLX04-OPhase 3Monoclonal antibodyVEGF-A

…and 16 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(4 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (3)
April 2027 (1)
Phase 4Recovery Period, AnesthesiaNot yet recruiting
Est. primary completion 2027-04-04 · NCT07239999 · CT.gov ↗
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July 2027 (1)
Phase 4Anesthesia, LocalNot yet recruiting
Est. primary completion 2027-07-01 · NCT07444827 · CT.gov ↗
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August 2027 (1)
Phase 4Knee Stiffness After Total Knee ArthroplastyRecruiting
Est. primary completion 2027-08 · NCT07348614 · CT.gov ↗
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2028 (1)
August 2028 (1)
Phase 3Knee ArthroscopyNot yet recruiting
Est. primary completion 2028-08-31 · NCT07674576 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (6)
Phase 2/3 (1)
Phase 2 (6)
Phase 1/2 (1)
Phase 1 (2)
Phase 4 (18)
Early phase / not applicable (6)