Asset profile

BAY1237592

Small molecule

Phase 1Soluble guanylate cyclaseNo recent registered activity
Weaksignal

Evidence outlook · lead readout

NCT03754660 · Hypertension, Pulmonary

The reported results come from study designs that frequently fail to replicate under controlled conditions — see the rationale below.

NCT03754660: This was an unblinded, non-randomized study with no placebo or active comparator arm; the treatment effect was measured against each patient's own baseline rather than a controlled comparison group, so the design cannot rule out other explanations for any change seen.

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