Asset profile

AV411

Small molecule

Preview Research free. Sign in to unlock 3 full asset or company pages every day, no card needed.Sign in to unlock this page
Ungradedevidence

Evidence outlook

Completed readouts not yet graded

This drug has completed mid- or late-stage studies whose evidence has not yet been graded on this platform. Where a sponsor has not posted registry results, topline data typically arrives via company announcements; see News.

Featured evidence outside covered markets:NCT04631471 · Myelopathy · Phase 3 · ungraded

How the evidence outlook works ↗

Competitive landscape

4 competitors in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 4 same-indication; 1 further along in development.

Unlock with Research ↗
DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
AV411: this drugPhase 3Small moleculePDE4 and PDE10; macrophage migration inhibitory factor (MIF)
Tofersen (Qalsody)ApprovedRNA / oligonucleotide—
UlefnersenPhase 3RNA / oligonucleotide—
CNM-Au8Phase 2/3Nanoparticlemitochondrial energy metabolism
DazucorilantPhase 2Small molecule—
Research

Unlock the full comparison

Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(2 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (1)
December 2026 (1)
Phase 2Alcohol Use Disorder (AUD), AlcoholismActive not recruiting
Est. primary completion 2026-12-31 · NCT05414240 · CT.gov ↗
What to watch
Unlock with Research ↗
2027 (1)
April 2027 (1)
Phase 2/3Amyotrophic Lateral SclerosisActive not recruiting
Est. primary completion 2027-04 · NCT04057898 · CT.gov ↗
What to watch
Unlock with Research ↗

See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (1)
Phase 2/3 (2)
Phase 2 (10)
Phase 1/2 (4)
Phase 1 (5)