Head-to-head evidence

TQH3906 vs WD-890

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Psoriasis

Shared mechanism: TYK2 · full Psoriasis pipeline

TQH3906

Developed by Sino Biopharmaceutical

Phase 3 in PsoriasisSmall molecule (oral TYK2 inhibitor)
Partial signal

NCT06542614 · Phase 2 · completed

This Phase 2 trial randomly assigned 209 people with plaque psoriasis to TQH3906 or placebo, with participants, carers, investigators and outcome assessors unaware of assignment. The primary measure was the proportion reaching PASI 75, a 75% improvement in psoriasis severity, at week 12. The sponsor reports more than 90% reaching PASI 75 and more than 70% reaching PASI 90 at the recommended dose, but gives no placebo figure and no statistical comparison, so the size of the advantage over placebo is not established by what has been released.

Next expected readout: September 2027 · NCT07724366 (registry estimate)

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WD-890

Developed by Ningbo/Zhejiang Wenda Pharma Technology Co.

Phase 3 in Psoriasissmall molecule
not yet graded

No graded featured trial for this indication yet; the grade above reflects that absence, not a judgment.

Next expected readout: November 2026 · NCT07672561 (registry estimate)

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: TQH3906's landscape · WD-890's landscape