Head-to-head evidence

Thalidomide vs TQB3820

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Multiple Myeloma

Shared mechanism: Cereblon E3 ubiquitin-ligase · full Multiple Myeloma pipeline

Thalidomide

Marketed by Bristol-Myers Squibb

Approved in Multiple Myelomasmall molecule (IMiD / cereblon modulator, first-generation)
Partial signal

NCT00083551 · Phase 3 · completed

The trial randomly assigned 323 participants to thalidomide and 345 to no thalidomide, but treatment was open-label rather than blinded. Its primary endpoint was the hard clinical outcome of six-year overall survival; although the reported percentages favored thalidomide, statistical significance cannot be determined from the posted registry data.

Next expected readout: August 2027 · NCT00572169 (registry estimate)

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TQB3820

Developed by Sino Biopharmaceutical

small molecule
not yet graded

No graded featured trial for this indication yet; the grade above reflects that absence, not a judgment.

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: Thalidomide's landscape · TQB3820's landscape