Head-to-head evidence

TE-8105 vs TG103

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Obesity

Shared mechanism: GLP-1 receptor · full Obesity pipeline

TE-8105

Developed by Immunwork

Phase 1/2 in Obesitypeptide
Weak signal

NCT06471530 · Phase 1/2 · completed

This was an open-label, non-randomized, dose-escalation study with no placebo or control group, so it cannot show whether any effect is attributable to the drug itself. Registry results were not posted at the time of grading; the key result shown was recovered from the cited external source.

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TG103

Developed by CSPC Pharmaceutical Group

Phase 3 in Obesityfusion protein
Partial signal

NCT05997576 · Phase 3 · completed

The study was randomized, double-blind, and placebo-controlled, with 675 participants and clinical primary outcomes measuring weight loss. However, no trial results are posted, so whether the primary endpoints were met cannot be determined.

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: TE-8105's landscape · TG103's landscape