Head-to-head evidence

Supaglutide vs XW014

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Type 2 Diabetes

Shared mechanism: GLP-1 receptor · full Type 2 Diabetes pipeline

Supaglutide

Developed by Shanghai Yinnuo Pharmaceutical Technology

Phase 2/3 in Type 2 Diabetespeptide
Reliable signal

NCT04998032 · Phase 2/3 · completed

In this randomized, double-blind, placebo-controlled Phase 2b/3 trial in 620 adults with type 2 diabetes already taking metformin, adding once-weekly supaglutide significantly lowered blood-sugar control (HbA1c) at 24 weeks compared with adding placebo, with a clearly significant treatment difference.

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XW014

Developed by Sciwind Biosciences

Phase 1 in Type 2 Diabetessmall molecule
Partial signal

NCT05579314 · Phase 1 · completed

This is a randomized, blinded, placebo-controlled trial, but its primary endpoints are adverse events and routine safety measurements rather than a diabetes outcome such as blood sugar control, and no results have been posted yet.

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: Supaglutide's landscape · XW014's landscape