Head-to-head evidence

Risperidone (QUAR) vs Risperidone (Risperdal)

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Schizophrenia

Shared mechanism: Dopamine D2 and serotonin 5-HT2A receptors (antagonist) · full Schizophrenia pipeline

Risperidone (QUAR)

Developed by Laboratorios Farmacéuticos Rovi, S.A.

Phase 3 in Schizophreniasmall molecule
Weak signal

NCT06276361 · Phase 1 · completed

A sequential, open-label pharmacokinetic study of quarterly-injection risperidone in 58 participants, with pharmacokinetic parameters as the primary measures. The design is uncontrolled for treatment effect and no results have been posted to the registry, so this is weak evidence.

Next expected readout: December 2027 · NCT07047651 (registry estimate)

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Risperidone (Risperdal)

Marketed by Johnson & Johnson

Approved in Schizophreniasmall molecule
Partial signal

NCT00253136 · Phase 3 · completed

The study randomized 458 participants to double-blind risperidone or placebo, with change in the clinical PANSS score as the primary endpoint. Because the registry does not report whether this endpoint was met, the trial provides a well-controlled design but no assessable result.

Next expected readout: December 2026 · NCT06482554 (registry estimate)

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: Risperidone (QUAR)'s landscape · Risperidone (Risperdal)'s landscape