Head-to-head evidence

RAY1225 vs tirzepatide

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Obesity

Shared mechanism: GLP-1/GIP receptor (dual) · full Obesity pipeline

RAY1225

Developed by Guangdong Raynovent Biotech

Phase 3 in Obesitypeptide
not yet graded

No graded featured trial for this indication yet; the grade above reflects that absence, not a judgment.

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tirzepatide · Zepbound / Mounjaro

Marketed by Eli Lilly

Approved in Obesitypeptide
Reliable signal

NCT04184622 · Phase 3 · completed

This was a large randomized, double-blind, placebo-controlled trial in 2,539 participants using percent change in body weight, the disease-defining endpoint for obesity, as the primary measure. All three tirzepatide doses produced significantly greater weight loss than placebo at 72 weeks.

Next expected readout: November 2026 · NCT07299084 (registry estimate)

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: RAY1225's landscape · tirzepatide's landscape