Head-to-head evidence

mesalamine (Apriso) vs mesalamine (Asacol)

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Ulcerative Colitis

Shared mechanism: Aminosalicylate · full Ulcerative Colitis pipeline

mesalamine (Apriso)

Marketed by Bausch Health

Approved in Ulcerative Colitis
not yet graded

No graded featured trial for this indication yet; the grade above reflects that absence, not a judgment.

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mesalamine (Asacol)

Marketed by AbbVie

Approved in Ulcerative Colitis
Reliable signal

NCT00073021 · Phase 3 · completed

The trial randomized and double-blinded participants and compared two Asacol doses in 268 patients with moderate disease analyzed for the primary endpoint. Its primary clinical and sigmoidoscopic treatment-success endpoint was met: 71.8% responded with 4.8 g/day versus 59.2% with 2.4 g/day (p=0.0357).

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: mesalamine (Apriso)'s landscape · mesalamine (Asacol)'s landscape