Head-to-head evidence

Lysergide tartrate (LSD) vs VLS-01

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Major Depressive Disorder

Shared mechanism: 5-HT2A receptor · full Major Depressive Disorder pipeline

Lysergide tartrate (LSD) · DT120

Developed by Definium Therapeutics

Phase 3 in Major Depressive Disordersmall molecule
Partial signal

NCT03866252 · Phase 2 · completed

Registry results were not posted at the time of grading; the key result shown was recovered from the cited external source.

Next expected readout: September 2027 · NCT07592689 (registry estimate)

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VLS-01

Developed by Eli Lilly and partners

Phase 2 in Major Depressive Disordersmall molecule
not yet graded

No graded featured trial for this indication yet; the grade above reflects that absence, not a judgment.

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: Lysergide tartrate (LSD)'s landscape · VLS-01's landscape