Head-to-head evidence

LY4050784 vs PRT3789

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Non-Small Cell Lung Cancer

Shared mechanism: SMARCA2 · full Non-Small Cell Lung Cancer pipeline

LY4050784

Developed by Foghorn Therapeutics Inc. under a licence from Eli Lilly

Phase 1 in Non-Small Cell Lung Cancersmall molecule
not yet graded

No graded featured trial for this indication yet; the grade above reflects that absence, not a judgment.

Next expected readout: October 2027 · NCT06561685 (registry estimate)

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PRT3789

Developed by Prelude Therapeutics

Phase 2 in Non-Small Cell Lung Cancerprotein degrader
Weak signal

NCT05639751 · Phase 1 · completed

Registry results were not posted at the time of grading; the key result shown was recovered from the cited external source.

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: LY4050784's landscape · PRT3789's landscape