Head-to-head evidence

LY03003 vs SER-252 (PEOZ-apomorphine)

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Parkinson's Disease

Shared mechanism: dopamine · full Parkinson's Disease pipeline

LY03003

Developed by Luye Pharma Group

Phase 3 in Parkinson's Diseasesmall molecule
Partial signal

NCT04571164 · Phase 3 · completed

The trial randomized 294 participants to LY03003 or placebo and masked participants, care providers, investigators, and outcome assessors. Its primary endpoint was change in the clinical UPDRS parts II+III score over 24 weeks, but the primary comparison and safety findings are not available, preventing assessment of whether the endpoint was met.

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SER-252 (PEOZ-apomorphine)

Developed by Serina Therapeutics

Phase 1 in Parkinson's Diseasesmall molecule
not yet graded

No graded featured trial for this indication yet; the grade above reflects that absence, not a judgment.

Next expected readout: January 2027 · NCT07422675 (registry estimate)

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: LY03003's landscape · SER-252 (PEOZ-apomorphine)'s landscape