Head-to-head evidence

liraglutide vs TG103

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Obesity

Shared mechanism: GLP-1 receptor · full Obesity pipeline

liraglutide · Saxenda / Victoza

Marketed by Novo Nordisk

Approved in Obesitypeptide
Reliable signal

NCT00781937 · Phase 3 · completed

The trial randomly assigned 212 participants to liraglutide and 210 to placebo in a double-blind, placebo-controlled design, with objective body-weight outcomes assessed at week 56. All three prespecified primary comparisons favored liraglutide and were statistically significant (each p<0.0001), supporting a strong evidence grade.

Next expected readout: December 2026 · NCT07225816 (registry estimate)

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TG103

Developed by CSPC Pharmaceutical Group

Phase 3 in Obesityfusion protein
Partial signal

NCT05997576 · Phase 3 · completed

The study was randomized, double-blind, and placebo-controlled, with 675 participants and clinical primary outcomes measuring weight loss. However, no trial results are posted, so whether the primary endpoints were met cannot be determined.

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: liraglutide's landscape · TG103's landscape