Head-to-head evidence
JR-131 vs RD01 (PEG-EPO)
Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.
Chronic Kidney Disease
Shared mechanism: Erythropoietin receptor (EPO-R) · full Chronic Kidney Disease pipeline
JR-131
Developed by Kissei Pharmaceutical
NCT02912494 · Phase 3 · completed
The study was double-blind and used an active darbepoetin alfa comparator, but the registry does not state whether participants were randomized or report the sample size. Its primary endpoint was change in hemoglobin, a surrogate measure. Registry results were not posted at the time of grading; the key result shown was recovered from the cited external source.
RD01 (PEG-EPO)
Developed by Shenzhen Sciprogen Bio-pharmaceutical
NCT04231292 · Phase 2 · status unknown
This is a randomized, controlled trial (active and placebo comparator arms) using hemoglobin concentration, the disease-defining measure for anemia, as its primary endpoint, but only participants were masked (not investigators or assessors), and no results have yet been posted.
The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: JR-131's landscape · RD01 (PEG-EPO)'s landscape