Head-to-head evidence

INV-202 vs monlunabant

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Obesity

Shared mechanism: CB1 receptor · full Obesity pipeline

INV-202

Developed by Inversago Pharma and partners

Phase 2 in Obesitysmall molecule
Partial signal

NCT05891834 · Phase 2 · completed

Randomized, double-blind Phase 1b trial (n=54) demonstrating significant weight loss with peripheral CB1 inverse agonist (Lancet Diabetes Endocrinol 2025).

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monlunabant

Developed by Novo Nordisk

Phase 1 in Obesitysmall molecule
Partial signal

NCT06542536 · Phase 1 · completed

The study was randomized and blinded against placebo, but it was conducted in healthy volunteers rather than people with obesity, and its purpose was pharmacokinetic bridging and safety, not proving a clinical effect. No results have been posted.

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: INV-202's landscape · monlunabant's landscape