Head-to-head evidence

HSK7653 vs Supaglutide

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Type 2 Diabetes

Shared mechanism: GLP-1 receptor · full Type 2 Diabetes pipeline

HSK7653

Developed by Haisco Pharmaceutical Group

Phase 3 in Type 2 Diabetessmall molecule
Reliable signal

NCT04556851 · Phase 3 · completed

This randomized, double-blind, placebo-controlled trial enrolled 476 patients and measured change in HbA1c, a standard efficacy measure in diabetes, at 24 weeks. Both HSK7653 doses lowered HbA1c significantly more than placebo (p<0.0001), meeting the trial's primary goal.

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Supaglutide

Developed by Shanghai Yinnuo Pharmaceutical Technology

Phase 2/3 in Type 2 Diabetespeptide
Reliable signal

NCT04998032 · Phase 2/3 · completed

In this randomized, double-blind, placebo-controlled Phase 2b/3 trial in 620 adults with type 2 diabetes already taking metformin, adding once-weekly supaglutide significantly lowered blood-sugar control (HbA1c) at 24 weeks compared with adding placebo, with a clearly significant treatment difference.

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: HSK7653's landscape · Supaglutide's landscape