Head-to-head evidence

HSK7653 vs SAL0150

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Type 2 Diabetes

Shared mechanism: GLP-1 receptor · full Type 2 Diabetes pipeline

HSK7653

Developed by Haisco Pharmaceutical Group

Phase 3 in Type 2 Diabetessmall molecule
Reliable signal

NCT04556851 · Phase 3 · completed

This randomized, double-blind, placebo-controlled trial enrolled 476 patients and measured change in HbA1c, a standard efficacy measure in diabetes, at 24 weeks. Both HSK7653 doses lowered HbA1c significantly more than placebo (p<0.0001), meeting the trial's primary goal.

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SAL0150

Developed by Shenzhen Salubris Pharmaceuticals

Phase 3 in Type 2 Diabetessmall molecule
Partial signal

NCT05782192 · Phase 3 · completed

The study was randomized, quadruple-masked, and included both active and placebo comparator groups, with 458 participants. Its primary endpoint was the surrogate measure of HbA1c change. Registry results were not posted at the time of grading; the key result shown was recovered from the cited external source.

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: HSK7653's landscape · SAL0150's landscape