Head-to-head evidence

HSK41959 vs IDE397

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Non-Small Cell Lung Cancer

Shared mechanism: MAT2A · full Non-Small Cell Lung Cancer pipeline

HSK41959

Developed by Haisco Pharmaceutical Group

Phase 1 in Non-Small Cell Lung Cancersmall molecule
not yet graded

No graded featured trial for this indication yet; the grade above reflects that absence, not a judgment.

Next expected readout: April 2029 · NCT07699757 (registry estimate)

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IDE397

Developed by IDEAYA Biosciences

Phase 1/2 in Non-Small Cell Lung Cancersmall molecule
Weak signal

NCT05975073 · Phase 1/2 · completed

The study is a nonrandomized, open-label, single-arm dose-exploration and dose-expansion trial without a placebo or active comparator. Its Part 2 primary outcome is objective tumor response by RECIST 1.1, but no results are posted, so whether the primary endpoint was met cannot be determined.

Next expected readout: April 2028 · NCT07277413 (registry estimate)

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: HSK41959's landscape · IDE397's landscape