Head-to-head evidence

HLX26 vs Relatlimab

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Non-Small Cell Lung Cancer

Shared mechanism: LAG-3 · full Non-Small Cell Lung Cancer pipeline

HLX26

Developed by Shanghai Henlius Biotech

Phase 2 in Non-Small Cell Lung Cancermonoclonal antibody
not yet graded

No graded featured trial for this indication yet; the grade above reflects that absence, not a judgment.

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Relatlimab

Marketed by Bristol-Myers Squibb

Phase 3 in Non-Small Cell Lung Cancermonoclonal antibody
Partial signal

NCT04623775 · Phase 2 · completed

The trial was randomized, triple-blind, and active-controlled, with 468 participants, and its primary efficacy endpoint was a clinical tumor-response measure. However, neither the Part 2 objective response comparison nor the Part 1 primary safety comparison was statistically significant, so the results provide well-designed but inconclusive evidence for relatlimab.

Next expected readout: January 2027 · NCT05176483 (registry estimate)

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: HLX26's landscape · Relatlimab's landscape