Head-to-head evidence

Hemay005 vs PALI-2108

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Ulcerative Colitis

Shared mechanism: PDE4 · full Ulcerative Colitis pipeline

Hemay005

Developed by Tianjin Hemay Pharmaceutical

Phase 3 in Ulcerative Colitissmall molecule
not yet graded

No graded featured trial for this indication yet; the grade above reflects that absence, not a judgment.

Next expected readout: December 2026 · NCT05486104 (registry estimate)

Unlock with Research ↗

PALI-2108

Developed by Palisade Bio

Phase 2 in Ulcerative ColitisSmall molecule (colon-targeted PDE4 inhibitor prodrug)
Partial signal

NCT06663605 · Phase 1 · completed

Most of this study randomized healthy volunteers to PALI-2108 or matching placebo under double-blind conditions, though the ulcerative colitis patient cohort was open-label. Registry results were not posted at the time of grading; the key result shown was recovered from the cited external source.

Next expected readout: October 2027 · NCT07845487 (registry estimate)

Unlock with Research ↗

The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: Hemay005's landscape · PALI-2108's landscape