Head-to-head evidence

HDG1901 vs HSK7653

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Type 2 Diabetes

Shared mechanism: GLP-1 receptor · full Type 2 Diabetes pipeline

HDG1901

Developed by Hangzhou Zhongmei Huadong Pharmaceutical

Phase 3 in Type 2 Diabetessmall molecule
Partial signal

NCT06739044 · Phase 3 · completed

The trial randomized 494 participants to HDG1901 or active Ozempic treatment, but neither participants nor investigators were blinded. Its primary endpoint was change in HbA1c, a surrogate measure, and the registry does not report whether the comparison met its objective, supporting a moderate evidence grade.

Caveat: source is secondary industry coverage that does not cite the trial registry number; attribution rests on sponsor/program match only.

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HSK7653

Developed by Haisco Pharmaceutical Group

Phase 3 in Type 2 Diabetessmall molecule
Reliable signal

NCT04556851 · Phase 3 · completed

This randomized, double-blind, placebo-controlled trial enrolled 476 patients and measured change in HbA1c, a standard efficacy measure in diabetes, at 24 weeks. Both HSK7653 doses lowered HbA1c significantly more than placebo (p<0.0001), meeting the trial's primary goal.

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: HDG1901's landscape · HSK7653's landscape