Head-to-head evidence

golimumab vs SOR102

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Ulcerative Colitis

Shared mechanism: TNF-alpha · full Ulcerative Colitis pipeline

golimumab · Simponi

Marketed by Johnson & Johnson and partners

Approved in Ulcerative Colitismonoclonal antibody (fully human IgG1)
Reliable signal

NCT01863771 · Phase 3 · completed

Design meets the 'strong' bar: randomized, double-blind (participant and investigator masked), placebo-controlled, phase 3, with a hard clinical endpoint (Mayo score-based clinical response); the primary comparison was clearly met in the favorable direction (18/32 vs 6/31, non-overlapping 95% CIs).

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SOR102

Developed by Sorriso Pharmaceuticals

Phase 1 in Ulcerative ColitisBiologic (oral dual TNFα/IL-23(p19) inhibitor)
Partial signal

NCT06080048 · Phase 1 · completed

Registry results were not posted at the time of grading; the key result shown was recovered from the cited external source.

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: golimumab's landscape · SOR102's landscape