Head-to-head evidence

EMB-01 vs MCLA-129

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Non-Small Cell Lung Cancer

Shared mechanism: EGFR x c-MET · full Non-Small Cell Lung Cancer pipeline

EMB-01

Marketed by Shanghai EpimAb Biotherapeutics

Phase 1/2 in Non-Small Cell Lung Cancerbispecific antibody
Weak signal

NCT03797391 · Phase 1/2 · status unknown

This was an open-label, non-randomized, single-arm dose-escalation and expansion study of EMB-01 in patients with advanced solid tumors, with no control group, so it cannot reliably show the drug's effect versus no treatment. Registry results were not posted at the time of grading; the key result shown was recovered from the cited external source.

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MCLA-129

Developed by Merus N.V. and partners

Phase 2 in Non-Small Cell Lung Cancerbispecific antibody
not yet graded

No graded featured trial for this indication yet; the grade above reflects that absence, not a judgment.

Next expected readout: April 2028 · NCT06885840 (registry estimate)

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: EMB-01's landscape · MCLA-129's landscape