Head-to-head evidence

elecoglipron vs ZT006

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Obesity

Shared mechanism: GLP-1 receptor · full Obesity pipeline

elecoglipron

Developed by AstraZeneca

Phase 3 in Obesitysmall molecule
Reliable signal

NCT06579092 · Phase 2 · completed

This randomised, triple-blind, placebo-controlled trial in 310 adults living with obesity or overweight reported a 10.5% reduction in body weight on elecoglipron 75 mg against 0.6% on placebo at 26 weeks. Percent weight change is the measure regulators accept as the primary efficacy endpoint in obesity.

Next expected readout: April 2028 · NCT07775404 (registry estimate)

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ZT006

Developed by Beijing QL Biopharmaceutical

Phase 2 in Obesitypeptide
Partial signal

NCT07307638 · Phase 1 · completed

This is a randomized, blinded, placebo-controlled trial, but its primary endpoints are adverse-event rates rather than a weight-loss outcome, and no results have been posted yet, so its effect on body weight is unknown.

Next expected readout: December 2026 · NCT07230132 (registry estimate)

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: elecoglipron's landscape · ZT006's landscape