Head-to-head evidence

elecoglipron vs Supaglutide

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Type 2 Diabetes

Shared mechanism: GLP-1 receptor · full Type 2 Diabetes pipeline

elecoglipron

Developed by AstraZeneca

Phase 3 in Type 2 Diabetessmall molecule
Reliable signal

NCT06579105 · Phase 2 · completed

Participants receiving AZD5004 or placebo were randomized and kept blinded to treatment; a semaglutide comparator arm was open-label but was not part of the primary comparison. The highest dose produced a substantially larger drop in HbA1c than placebo, meeting the trial's main goal.

Next expected readout: May 2028 · NCT07664553 (registry estimate)

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Supaglutide

Developed by Shanghai Yinnuo Pharmaceutical Technology

Phase 2/3 in Type 2 Diabetespeptide
Reliable signal

NCT04998032 · Phase 2/3 · completed

In this randomized, double-blind, placebo-controlled Phase 2b/3 trial in 620 adults with type 2 diabetes already taking metformin, adding once-weekly supaglutide significantly lowered blood-sugar control (HbA1c) at 24 weeks compared with adding placebo, with a clearly significant treatment difference.

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: elecoglipron's landscape · Supaglutide's landscape