Head-to-head evidence

efsubaglutide alfa vs TG103

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Obesity

Shared mechanism: GLP-1 receptor · full Obesity pipeline

efsubaglutide alfa

Developed by Shanghai Yinnuo Pharmaceutical Technology

Phase 2/3 in Obesityprotein (Fc-fusion)
Partial signal

NCT06732960 · Phase 2 · completed

The study was randomized, double-blind, and placebo-controlled, but each dose cohort was small, with approximately 10 participants per cohort and a 8:2 active-to-placebo allocation. Because the registry provides no primary endpoint results, it is not possible to determine whether the weight-loss comparison was met.

Next expected readout: November 2026 · NCT07163650 (registry estimate)

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TG103

Developed by CSPC Pharmaceutical Group

Phase 3 in Obesityfusion protein
Partial signal

NCT05997576 · Phase 3 · completed

The study was randomized, double-blind, and placebo-controlled, with 675 participants and clinical primary outcomes measuring weight loss. However, no trial results are posted, so whether the primary endpoints were met cannot be determined.

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: efsubaglutide alfa's landscape · TG103's landscape