Head-to-head evidence

efsubaglutide alfa vs liraglutide

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Obesity

Shared mechanism: GLP-1 receptor · full Obesity pipeline

efsubaglutide alfa

Developed by Shanghai Yinnuo Pharmaceutical Technology

Phase 2/3 in Obesityprotein (Fc-fusion)
Partial signal

NCT06732960 · Phase 2 · completed

The study was randomized, double-blind, and placebo-controlled, but each dose cohort was small, with approximately 10 participants per cohort and a 8:2 active-to-placebo allocation. Because the registry provides no primary endpoint results, it is not possible to determine whether the weight-loss comparison was met.

Next expected readout: November 2026 · NCT07163650 (registry estimate)

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liraglutide · Saxenda / Victoza

Marketed by Novo Nordisk

Approved in Obesitypeptide
Reliable signal

NCT00781937 · Phase 3 · completed

The trial randomly assigned 212 participants to liraglutide and 210 to placebo in a double-blind, placebo-controlled design, with objective body-weight outcomes assessed at week 56. All three prespecified primary comparisons favored liraglutide and were statistically significant (each p<0.0001), supporting a strong evidence grade.

Next expected readout: December 2026 · NCT07225816 (registry estimate)

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: efsubaglutide alfa's landscape · liraglutide's landscape