Head-to-head evidence

Divozilimab vs Ublituximab

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Multiple Sclerosis

Shared mechanism: CD20 · full Multiple Sclerosis pipeline

Divozilimab

Developed by Biocad

Phase 3 in Multiple Sclerosismonoclonal antibody
Partial signal

NCT06987851 · Phase 3 · completed

This was an open-label, single-group extension study without a comparator, enrolling 44 participants who continued from the prior BCD-132-4/MIRANTIBUS study after earlier BCD-132 treatment. Its primary endpoint was the clinical measure of annualized relapse rate at 48 and 96 weeks, but the result was not reported.

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Ublituximab

Marketed by TG THERAPEUTICS, INC.

Approved in Multiple Sclerosismonoclonal antibody
Reliable signal

NCT03277261 · Phase 3 · completed

This was a randomized, quadruple-masked, active-controlled trial of 549 participants, with ublituximab and teriflunomide administered alongside matching placebos. The primary clinical endpoint was met: ublituximab produced a significantly lower annualized relapse rate than teriflunomide through 96 weeks (p<0.0001).

Next expected readout: October 2026 · NCT07211633 (registry estimate)

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: Divozilimab's landscape · Ublituximab's landscape