Head-to-head evidence

DD01 vs efsubaglutide alfa

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Obesity

Shared mechanism: GLP-1 receptor · full Obesity pipeline

DD01

Developed by D&D Pharmatech and partners

Phase 2 in Obesitypeptide
Partial signal

NCT06410924 · Phase 2 · completed

This randomized, triple-blind, placebo-controlled Phase 2 trial enrolled 67 people with fatty liver disease and measured the proportion who achieved at least a 30% reduction in liver fat, measured by MRI scan, after 12 weeks. DD01 met this imaging-based endpoint far more often than placebo (75.8% vs 11.8%), though liver-fat reduction on imaging is an earlier marker of benefit rather than the biopsy-confirmed liver-disease improvement that later-stage trials assess.

Caveat: this result is taken from a company announcement or a news report of one, not from the trial registry or a peer-reviewed publication. Treat the figures as the sponsor's own statement, not as independently verified evidence.

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efsubaglutide alfa

Developed by Shanghai Yinnuo Pharmaceutical Technology

Phase 2/3 in Obesityprotein (Fc-fusion)
Partial signal

NCT06732960 · Phase 2 · completed

The study was randomized, double-blind, and placebo-controlled, but each dose cohort was small, with approximately 10 participants per cohort and a 8:2 active-to-placebo allocation. Because the registry provides no primary endpoint results, it is not possible to determine whether the weight-loss comparison was met.

Next expected readout: November 2026 · NCT07163650 (registry estimate)

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: DD01's landscape · efsubaglutide alfa's landscape