Head-to-head evidence

DA-302168S vs XW003

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Obesity

Shared mechanism: GLP-1 receptor · full Obesity pipeline

DA-302168S

Developed by Chendu DIAO Pharmaceutical Group

Phase 3 in Obesitysmall molecule
Partial signal

NCT06953063 · Phase 2 · completed

The trial was randomized, quadruple-blind, placebo-controlled, and enrolled 250 participants, with percentage change in body weight as a clinical primary endpoint. However, results are not posted, so it is not possible to determine whether the primary comparison was met; the available evidence therefore supports a moderate grade rather than a strong one.

Next expected readout: July 2027 · NCT07629544 (registry estimate)

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XW003

Developed by Sciwind Biosciences

Phase 3 in Obesitypeptide
Reliable signal

NCT05813795 · Phase 3 · completed

This randomized, triple-blind, placebo-controlled Phase 3 trial (n=664) in adults with overweight or obesity found that ecnoglutide (XW003) produced significantly greater weight loss than placebo at 40 weeks across all three doses tested, up to 13.2% versus about 0.1% with placebo (p<0.0001 for every dose).

Caveat: this result is taken from a company announcement or a news report of one, not from the trial registry or a peer-reviewed publication. Treat the figures as the sponsor's own statement, not as independently verified evidence.

Next expected readout: February 2027 · NCT07073417 (registry estimate)

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: DA-302168S's landscape · XW003's landscape