Head-to-head evidence

DA-302168S vs VCT220

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Obesity

Shared mechanism: GLP-1 receptor · full Obesity pipeline

DA-302168S

Developed by Chendu DIAO Pharmaceutical Group

Phase 3 in Obesitysmall molecule
Partial signal

NCT06953063 · Phase 2 · completed

The trial was randomized, quadruple-blind, placebo-controlled, and enrolled 250 participants, with percentage change in body weight as a clinical primary endpoint. However, results are not posted, so it is not possible to determine whether the primary comparison was met; the available evidence therefore supports a moderate grade rather than a strong one.

Next expected readout: July 2027 · NCT07629544 (registry estimate)

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VCT220

Developed by Ji Xing Pharmaceuticals (CORXEL) under a licence from Vincentage Pharma

Phase 3 in Obesitysmall molecule
Reliable signal

NCT06569355 · Phase 2 · completed

This Phase 2 trial randomly assigned 250 people with obesity or overweight to one of several VCT220 doses or placebo, with participants, carers, investigators and outcome assessors unaware of assignment. The primary measure was percentage change in body weight at week 16. Weight fell by between 5.8% and 9.7% across the VCT220 dose groups against 1.6% on placebo, with reductions of 9.7% and 9.4% at the two 160 mg schedules (p of 0.001 or lower).

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: DA-302168S's landscape · VCT220's landscape