Head-to-head evidence

DA-302168S vs elecoglipron

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Obesity

Shared mechanism: GLP-1 receptor · full Obesity pipeline

DA-302168S

Developed by Chendu DIAO Pharmaceutical Group

Phase 3 in Obesitysmall molecule
Partial signal

NCT06953063 · Phase 2 · completed

The trial was randomized, quadruple-blind, placebo-controlled, and enrolled 250 participants, with percentage change in body weight as a clinical primary endpoint. However, results are not posted, so it is not possible to determine whether the primary comparison was met; the available evidence therefore supports a moderate grade rather than a strong one.

Next expected readout: July 2027 · NCT07629544 (registry estimate)

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elecoglipron

Developed by AstraZeneca

Phase 3 in Obesitysmall molecule
Reliable signal

NCT06579092 · Phase 2 · completed

This randomised, triple-blind, placebo-controlled trial in 310 adults living with obesity or overweight reported a 10.5% reduction in body weight on elecoglipron 75 mg against 0.6% on placebo at 26 weeks. Percent weight change is the measure regulators accept as the primary efficacy endpoint in obesity.

Next expected readout: April 2028 · NCT07775404 (registry estimate)

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: DA-302168S's landscape · elecoglipron's landscape