Head-to-head evidence

CJC-1134-PC vs PEX168

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Type 2 Diabetes

Shared mechanism: GLP-1 receptor · full Type 2 Diabetes pipeline

CJC-1134-PC

Developed by ConjuChem

Phase 3 in Type 2 Diabetespeptide
Partial signal

NCT07058545 · Phase 3 · completed

The study randomized 474 participants to CJC-1134-PC or placebo and blinded participants, care providers, investigators, and outcome assessors. Its primary endpoint was change in HbA1c at Week 25, a surrogate measure, and the registry does not report whether the comparison was favorable or statistically significant.

Caveat: this result is taken from a company announcement or a news report of one, not from the trial registry or a peer-reviewed publication. Treat the figures as the sponsor's own statement, not as independently verified evidence.

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PEX168

Developed by Jiangsu Hengrui Pharmaceuticals and partners

Phase 3 in Type 2 Diabetespeptide
Reliable signal

NCT02477969 · Phase 3 · status unknown

This was a randomized, triple-blind, placebo-controlled trial with 587 participants, testing PEX168 against placebo, both added to metformin, using change in HbA1c as the primary measure. A published report of the trial's results describes the primary endpoint as met, with substantially more PEX168 patients than placebo patients reaching HbA1c targets at 24 weeks.

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: CJC-1134-PC's landscape · PEX168's landscape