Head-to-head evidence

CJC-1134-PC vs efpeglenatide

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Type 2 Diabetes

Shared mechanism: GLP-1 receptor · full Type 2 Diabetes pipeline

CJC-1134-PC

Developed by ConjuChem

Phase 3 in Type 2 Diabetespeptide
Partial signal

NCT07058545 · Phase 3 · completed

The study randomized 474 participants to CJC-1134-PC or placebo and blinded participants, care providers, investigators, and outcome assessors. Its primary endpoint was change in HbA1c at Week 25, a surrogate measure, and the registry does not report whether the comparison was favorable or statistically significant.

Caveat: this result is taken from a company announcement or a news report of one, not from the trial registry or a peer-reviewed publication. Treat the figures as the sponsor's own statement, not as independently verified evidence.

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efpeglenatide

Developed by Hanmi Pharmaceutical and partners

Phase 3 in Type 2 Diabetespeptide
Partial signal

NCT03353350 · Phase 3 · completed

The trial was randomized, quadruple-blinded, placebo-controlled, and included 406 participants, providing a strong comparative design. However, the primary endpoint was the surrogate measure of HbA1c change, and although the reported changes favored efpeglenatide, statistical significance for the primary comparison was not reported.

Next expected readout: November 2027 · NCT07379333 (registry estimate)

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: CJC-1134-PC's landscape · efpeglenatide's landscape