Head-to-head evidence
CID-103 vs Daratumumab
Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.
Multiple Myeloma
Shared mechanism: CD38 · full Multiple Myeloma pipeline
CID-103
Developed by CASI Pharmaceuticals, Inc.
NCT04758767 · Phase 1 · completed
All participants received CID-103 with no placebo or comparator arm and no blinding, so the design cannot show whether the antibody works better than another option. Registry results were not posted at the time of grading; the key result shown was recovered from the cited external source.
Daratumumab
Marketed by Johnson & Johnson
NCT02076009 · Phase 3 · completed
This was a large randomized, open-label trial with an active comparator, enrolling 286 participants in the daratumumab group and 283 in the control group. Progression-free survival was the hard clinical primary endpoint, but the registry does not report a complete treatment comparison or statistical significance for it, so the result cannot be clearly classified as met.
Next expected readout: October 2026 · NCT06140966 (registry estimate)
The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: CID-103's landscape · Daratumumab's landscape