Head-to-head evidence
BMF-500 vs Gilteritinib
Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.
Acute Myeloid Leukemia
Shared mechanism: FLT3 · full Acute Myeloid Leukemia pipeline
BMF-500
Developed by Biomea Fusion
No graded featured trial for this indication yet; the grade above reflects that absence, not a judgment.
Gilteritinib
Marketed by Astellas Pharma
NCT02997202 · Phase 3 · completed
This was a randomized, quadruple-blind, placebo-controlled trial with 178 participants per group and a hard clinical primary endpoint of relapse-free survival. The primary endpoint was not statistically significant (hazard ratio 0.679; p=0.0518), so the results provide well-controlled but inconclusive evidence of benefit.
Next expected readout: December 2026 · NCT06001788 (registry estimate)
The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: BMF-500's landscape · Gilteritinib's landscape