Head-to-head evidence

Anti-CD33 CAR T-cells vs PRGN-3006 T Cells

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Acute Myeloid Leukemia

Shared mechanism: CD33 · full Acute Myeloid Leukemia pipeline

Anti-CD33 CAR T-cells

Developed by iCell Gene Therapeutics

Phase 1/2 in Acute Myeloid Leukemiabiologic (registry-typed, subtype undisclosed)
Weak signal

NCT01864902 · Phase 1/2 · status unknown

This was a small, single-arm, open-label study with no comparator group, designed primarily to assess safety of this cell therapy in a heavily pretreated leukemia population. Results have not yet been posted.

Next expected readout: September 2028 · NCT05672147 (registry estimate)

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PRGN-3006 T Cells

Developed by Precigen, Inc

Phase 1 in Acute Myeloid LeukemiaCAR-T cell therapy
not yet graded

No graded featured trial for this indication yet; the grade above reflects that absence, not a judgment.

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: Anti-CD33 CAR T-cells's landscape · PRGN-3006 T Cells's landscape