Head-to-head evidence

Anti-CD33 CAR T-cells vs BL-M11D1

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Acute Myeloid Leukemia

Shared mechanism: CD33 · full Acute Myeloid Leukemia pipeline

Anti-CD33 CAR T-cells

Developed by iCell Gene Therapeutics

Phase 1/2 in Acute Myeloid Leukemiabiologic (registry-typed, subtype undisclosed)
Weak signal

NCT01864902 · Phase 1/2 · status unknown

This was a small, single-arm, open-label study with no comparator group, designed primarily to assess safety of this cell therapy in a heavily pretreated leukemia population. Results have not yet been posted.

Next expected readout: September 2028 · NCT05672147 (registry estimate)

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BL-M11D1

Developed by SystImmune

Phase 2/3 in Acute Myeloid Leukemiaantibody-drug conjugate
not yet graded

No graded featured trial for this indication yet; the grade above reflects that absence, not a judgment.

Next expected readout: December 2026 · NCT05924750 (registry estimate)

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: Anti-CD33 CAR T-cells's landscape · BL-M11D1's landscape