Head-to-head evidence

Ambroxol vs GT-02287

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Parkinson's Disease

Shared mechanism: GBA1/glucocerebrosidase · full Parkinson's Disease pipeline

Ambroxol

Developed by Agyany Pharma Ltd

Phase 3 in Parkinson's Diseasesmall molecule
Partial signal

NCT05830396 · Phase 2/3 · status unknown

This is a randomized, placebo-controlled trial with full blinding of participants, care providers, and assessors, using a validated Parkinson's motor rating scale as its primary endpoint. Results have not yet been posted, so whether ambroxol improved motor outcomes compared with placebo is not yet known.

Next expected readout: February 2029 · NCT05778617 (registry estimate)

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GT-02287

Developed by Gain Therapeutics, Inc.

Phase 2 in Parkinson's Diseasesmall molecule
not yet graded

No graded featured trial for this indication yet; the grade above reflects that absence, not a judgment.

Next expected readout: June 2028 · NCT07280299 (registry estimate)

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: Ambroxol's landscape · GT-02287's landscape