Head-to-head evidence

ALX2004 vs AZD3759

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Non-Small Cell Lung Cancer

Shared mechanism: EGFR · full Non-Small Cell Lung Cancer pipeline

ALX2004

Developed by ALX Oncology Inc.

Phase 1 in Non-Small Cell Lung Cancerantibody-drug conjugate
not yet graded

No graded featured trial for this indication yet; the grade above reflects that absence, not a judgment.

Next expected readout: June 2027 · NCT07085091 (registry estimate)

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AZD3759

Developed by AstraZeneca and partners

Phase 2/3 in Non-Small Cell Lung Cancersmall molecule
Partial signal

NCT03653546 · Phase 2/3 · completed

The trial randomized 492 participants to AZD3759 or active treatment with erlotinib or gefitinib, with progression-free survival assessed by independent central radiology as the primary endpoint. Registry results were not posted at the time of grading; the key result shown was recovered from the cited external source.

Next expected readout: April 2028 · NCT07361705 (registry estimate)

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: ALX2004's landscape · AZD3759's landscape