Head-to-head evidence

ALX2004 vs Ametinib

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Non-Small Cell Lung Cancer

Shared mechanism: EGFR · full Non-Small Cell Lung Cancer pipeline

ALX2004

Developed by ALX Oncology Inc.

Phase 1 in Non-Small Cell Lung Cancerantibody-drug conjugate
not yet graded

No graded featured trial for this indication yet; the grade above reflects that absence, not a judgment.

Next expected readout: June 2027 · NCT07085091 (registry estimate)

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Ametinib

Developed by Hansoh Pharmaceutical Group and partners

Phase 2 in Non-Small Cell Lung Cancersmall molecule
Weak signal

NCT05754736 · Phase 2 · status unknown

This is a single-arm, open-label study with no comparator group, so there is no way to know whether the combination performs better than existing treatments. Results on tumor response and progression-free survival have not yet been posted.

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: ALX2004's landscape · Ametinib's landscape