Head-to-head evidence

Alirocumab vs QLC7401

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Atherosclerotic Cardiovascular Disease

Shared mechanism: PCSK9 · full Atherosclerotic Cardiovascular Disease pipeline

Alirocumab · Praluent

Marketed by Regeneron Pharmaceuticals

Approved in Atherosclerotic Cardiovascular Diseasemonoclonal antibody
Partial signal

NCT01507831 · Phase 3 · completed

The study was large (2,341 participants), randomized, quadruple-blind, and placebo-controlled. Its primary clinical safety endpoint was reported, but the registry does not provide a statistical significance test for the comparison, so whether the primary endpoint was met cannot be determined.

Next expected readout: December 2026 · NCT07477704 (registry estimate)

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QLC7401

Developed by Qilu Pharmaceutical

Phase 3 in Atherosclerotic Cardiovascular DiseaseRNAi (siRNA)
not yet graded

No graded featured trial for this indication yet; the grade above reflects that absence, not a judgment.

Next expected readout: October 2027 · NCT07444086 (registry estimate)

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: Alirocumab's landscape · QLC7401's landscape