Head-to-head evidence

AFFITOPE PD01A / ACI-7104.056 vs UCB7853

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Parkinson's Disease

Shared mechanism: alpha-synuclein · full Parkinson's Disease pipeline

AFFITOPE PD01A / ACI-7104.056

Developed by AC Immune

Phase 2 in Parkinson's Diseasevaccine
not yet graded

No graded featured trial for this indication yet; the grade above reflects that absence, not a judgment.

Next expected readout: January 2028 · NCT06015841 (registry estimate)

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UCB7853

Developed by UCB

Phase 1 in Parkinson's Diseasebiologic
Partial signal

NCT04651153 · Phase 1 · completed

This was a randomized, quadruple-blind, placebo-controlled study, a sound design for an early safety trial that included both healthy volunteers and Parkinson's disease patients, but its only endpoints were safety-related, and results are not yet posted.

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: AFFITOPE PD01A / ACI-7104.056's landscape · UCB7853's landscape